Anaphylactic Shock Caused by the Epidurally-Administered Hyalurinidase

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Anaphylactic Shock Caused by the Epidurally-Administered Hyalurinidase

Hyaluronidase is an enzyme that has temporary and reversible enzymatic effects on the matrix of connective tissue. When added to local anesthetics in pain treatments, it enhances their infiltration and dispersal into tissues. It is widely used in anesthesia for ocular, dental, and plastic surgery. Reports of drug hypersensitivity to hyaluronidase are rare and are usually confined to peribulbar ...

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Anaphylactic shock caused by impurities in orgotein preparations.

Previously reported allergic reactions to orgotein (superoxide dismutase) injections has assigned responsibility to this molecule, which is obtained from bovine liver. We report an anaphylactic shock probably caused by impurities contained in an orgotein preparation. Prick test to Peroxinorm (orgotein), BSA, and cow liver extract were positive but resulted negative with chymotrypsin, milk, meat...

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ژورنال

عنوان ژورنال: The Korean Journal of Pain

سال: 2011

ISSN: 2005-9159,2093-0569

DOI: 10.3344/kjp.2011.24.4.221